Das Leibniz-Institut zur Analyse des Biodiversitätswandels

ist ein Forschungsmuseum der Leibniz Gemeinschaft

  • DE
  • EN
  • LS

Protein phosphatases: Function, selectivity, and chemical modulation

Termin: 
Mo, 09.01.2023 - 17:15 Uhr
Treffpunkt: 
Online-Lecture via Zoom (Zugangs-Link erhältlich bei: vonderemde@uni-bonn.de)
Veranstaltungsart: 
Vortrag
Veranstaltungsreihe: 
Evolutionsbiologisches Kolloquium
Zielgruppe: 
Erwachsene
Vortragende / Vortragender: 
Prof. Dr. Maja Banks-Köhn, BIOSS and Institute of Biology III, University of Freiburg

Counteracting kinase activity, phosphatases are essential for cellular processes, yet still understudied. We employ as well as develop approaches to study phosphatases using interdisciplinary methods ranging from synthetic chemistry to molecular and cell biology. I will give an overview about our work, including studies on substrates and the chemical modulation of protein phosphatase-1 with an application in cardiomyopathy, contributions to understanding and inhibiting the cancer-promoting phosphatase PRL-3, and the elucidation of the activation of the oncogenic phosphatase SHP2 in the cell death receptor PD-1 pathway, which plays an important role in cancer immune evasion.

Angebote

Mo Di Mi Do Fr Sa So
 
 
 
 
 
 
1
 
2
 
3
 
4
 
5
 
6
 
7
 
8
 
 
10
 
11
 
12
 
13
 
14
 
15
 
 
17
 
 
19
 
20
 
21
 
22
 
 
24
 
25
 
26
 
27
 
28
 
29
 
 
31