The Leibniz Institute for the Analysis of Biodiversity Change

is a research museum of the Leibniz Association

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Credit Simon Sommerfeld, Phoxinus phoxinus, Sülz

Junior Research Group (Minnow)

Reiter

Info

In biodiversity research, little is known so far about how hybridizations of a native and a non-native species can lead to the evolution of an invasive hybrid. A group of researchers led by Dr Madlen Stange is now studying this aspect in a project at the Zoological Research Museum Alexander Koenig – Leibniz Institute for Animal Biodiversity (ZFMK). The group is investigating the spread of Phoxinus, an ecologically important schooling fish, in the River Sieg, a 155 km tributary of the River Rhine.

Staff

Scientist, third-party funded

Dr. Madlen Stange

HEAD of Junior Research Group "Minnow"

Tel: +49 228 9122-367

Fax: +49 228 9122-212

E-Mail: M.Stange [at] leibniz-lib.de

Ph.D. student

Temitope Oriowo

PhD student

Tel: +49 228 9122-368

E-Mail: T.Oriowo [at] leibniz-lib.de

PhD Student

Tel: +49 228 9122-368

E-Mail: n.sternberg [at] leibniz-lib.de

Projects

2021

Hybrid swarm evolution in minnows

In biodiversity research, little is known so far about how hybridizations of a native and a non-native species can lead to the evolution of an invasive hybrid. A group of researchers led by Dr Madlen Stange is now studying this aspect in a project at the Zoological Research Museum Alexander Koenig – Leibniz Institute for Animal Biodiversity (ZFMK). The group is investigating the spread of Phoxinus, an ecologically important schooling fish, in the River Sieg, a 155 km tributary of the River Rhine.

Project lead:

Dr. Madlen Stange

Funding:

Leibniz Association

Publications

Published in

2023

Oriowo T, Chrysostomakis I, Martin S, Kukowka S, Brown T, Winkler S, Myers EW, Böhne A and Stange M. (2023) A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus) provide evidence of haplotype diversity. bioRxiv 2023.11.30.569369. doi: 10.1101/2023.11.30.569369

Links:

A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus)

2022

Bishop, C.E., Gahm K., Hendry, A.P., Jones, S.E., Stange, M., Solomon, C.T. (2022): Benthic–limnetic morphological variation in fishes: Dissolved organic carbon concentration produces unexpected patterns - Ecosphere (13): e3965. doi:10.1002/ecs2.3965

Brüningk, S. C. , Klatt, J., Stange, M., Mari, A., Brunner, M., Roloff, T-C., et al. (2022): Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area. Virus Evolution 8(1): veac002. doi:10.1093/ve/veac002

Kathrin Zürcher, Irene A Abela, Madlen Stange, Carole Dupont, Catrina Mugglin, Adrian Egli, Alexandra Trkola, Matthias Egger, Lukas Fenner, Alpha variant coronavirus outbreak in a nursing home despite high vaccination coverage: molecular, epidemiological and immunological studies, Clinical Infectious Diseases, 2022;, ciab1005, https://doi.org/10.1093/cid/ciab1005

Nadeau, S. A., Vaughan, T. G., Beckmann, C., Topolsky, I., Chen, C., Hodcroft, E., Schär, T., Nissen, I., Santacroce, N., Burcklen, E., Ferreira, P., Jablonski, K. P., Posada-Céspedes, S., Capece, V., Seidel, S., Santamaria de Souza, N., Martinez-Gomez, J. M., Cheng, P., Bosshard, P. P., Levesque, M. P., Kufner, V., Schmutz, S., Zaheri, M., Huber, M., Trkola, A., Cordey, S., Laubscher, F., Gonçalves, A. R., Aeby, S., Pillonel, T., Jacot, D., Bertelli, C., Greub, G., Leuzinger, K., Stange, M., Mari, A., Roloff, T., Seth-Smith, H., Hirsch, H. H., Egli, A., Redondo, M., Kobel, O., Noppen, C., du Plessis, L., Beerenwinkel, N., Neher, R. A., Beisel, C., Stadler, T. Swiss Public Health Measures Associated with Reduced SARS-CoV-2 Transmission Using Genome Data. Science Translational Medicine 2022, eabn7979. https://doi.org/10.1126/scitranslmed.abn7979.

2021

Wegner, F., Roloff, T., Huber, M., Cordey, S., Ramette, A., Gerth, Y., Bertelli, C., Stange, M., Seth-Smith, H., Mari, A., Leuzinger, K., Cerutti, L., Harshman, K., Xenarios, I., Le Mercier, P., Bittel, P., Neuenschwander, S., Opota, O., Fuchs, J., Panning, M., … Egli, A. (2021). External quality assessment of SARS-CoV-2-sequencing: An ESGMD-SSM pilot trial across 15 European laboratories. Journal of clinical microbiology, JCM0169821. Advance online publication. https://doi.org/10.1128/JCM.01698-21

Chen, C., Nadeau, S. A., Topolsky, I., Manceau, M., Huisman, J. S., Jablonski, K. P., Fuhrmann, L., ..., Stange, M., et. al. (2021): Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland. Epidemics, 37, 100480. https://doi.org/10.1016/j.epidem.2021.100480

Goncalves Cabecinhas, A.R., Roloff, T., Stange, M., Bertelli, C., Huber, M., Ramette, A., Chen, C., et. al. (2021): SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021—Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms, 9, 677. https://doi.org/10.3390/microorganisms9040677

Fox J, Jiménez M.A., Stange M. Natural history study of an understudied sea catfish species from Panama (Siluriformes: Ariidae). Neotrop Ichthyol. 2021; 19(4):e200105. https://doi.org/10.1590/1982-0224-2020-0105

Mari, A., Roloff, T., Stange, M., Søgaard, K.K., Asllanaj, E., Tauriello, G., Alexander, et. al. (2021): A. Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance. Microorganisms, 9, 1094. https://doi.org/10.3390/microorganisms9051094

Stange, M., Barrett, R.D.H. & Hendry, A.P. The importance of genomic variation for biodiversity, ecosystems and people. Nat Rev Genet 22, 89–105 (2021). https://doi.org/10.1038/s41576-020-00288-7

Stange, M., Mari, A., Roloff, T., Seth-Smith, H. M. B., Schweitzer, M., Brunner, M., Leuzinger, K., et al. (2021) SARS-CoV-2 outbreak in a tri-national urban area is dominated by a B.1 lineage variant linked to a mass gathering event. PLOS Pathogens 17(3): e1009374. https://doi.org/10.1371/journal.ppat.1009374

2019

Heck, L., Sanchez-Villagra, M. R., Stange, M. (2019): Why the long face? Comparative shape analysis of miniature, pony, and other horse skulls reveals changes in ontogenetic growth. PeerJ 7:e7678 https://doi.org/10.7717/peerj.7678

2018

Heck, L., Wilson, L. A. B., Evin, A., Stange, M., Sánchez-Villagra, M. R. (2018): Shape variation and modularity of skull and teeth in domesticated horses and wild equids. Front Zool 15, 14. https://doi.org/10.1186/s12983-018-0258-9

Stange, M., Aguirre-Fernández, G., Salzburger, W., Sánchez-Villagra, M.R. (2018): Study of morphological variation of northern Neotropical Ariidae reveals conservatism despite macrohabitat transitions. BMC Evol Biol 18, 38 (2018). https://doi.org/10.1186/s12862-018-1152-y

Stange, M., Núñez-León, D., Sánchez-Villagra, M. R., Jensen, P., & Wilson, L. A. B. (2018): Morphological variation under domestication: how variable are chickens? Royal Society Open Science, 5(8), 180993. https://doi.org/10.1098/rsos.180993

Stange, M., Sánchez-Villagra, M. R., Salzburger, W., & Matschiner, M. (2018): Bayesian Divergence-Time Estimation with Genome-Wide Single-Nucleotide Polymorphism Data of Sea Catfishes (Ariidae) Supports Miocene Closure of the Panamanian Isthmus, Systematic Biology, Volume 67, Issue 4, 681–699, https://doi.org/10.1093/sysbio/syy006

2016

Stange, M., Aguirre-Fernández, G., Cooke, R.G., Barros, T., Salzburger, W. and Sánchez-Villagra, M.R. (2016), Evolution of opercle bone shape along a macrohabitat gradient: species identification using mtDNA and geometric morphometric analyses in neotropical sea catfishes (Ariidae). Ecol Evol, 6: 5817-5830. https://doi.org/10.1002/ece3.2334

2015

Fuchs, M., Geiger, M., Stange, M., Sánchez-Villagra, M. R. (2015): Growth trajectories in the cave bear and its extant relatives: an examination of ontogenetic patterns in phylogeny. BMC Evol Biol 15, 239. https://doi.org/10.1186/s12862-015-0521-z

2013

Mateus, C. S., Stange, M., Berner, D., Roesti, M., Quintella, B. R., Alves, M. J., Almeida, P. R., & Salzburger, W. (2013): Strong genome-wide divergence between sympatric European river and brook lampreys. Current Biology, 23(15), R649–R650. https://doi.org/10.1016/j.cub.2013.06.026