The Leibniz Institute for the Analysis of Biodiversity Change

is a research museum of the Leibniz Association

Link to Leibniz Association

DE
EN
LS

Credit Simon Sommerfeld, Phoxinus phoxinus, Sülz

Junior Research Group (Minnow)

Reiter

Info

In biodiversity research, little is known so far about how hybridizations of a native and a non-native species can lead to the evolution of an invasive hybrid. A group of researchers led by Dr Madlen Stange is now studying this aspect in a project at the Zoological Research Museum Alexander Koenig – Leibniz Institute for Animal Biodiversity (ZFMK). The group is investigating the spread of Phoxinus, an ecologically important schooling fish, in the River Sieg, a 155 km tributary of the River Rhine.

Staff

Scientist, third-party funded

Dr. Madlen Stange

HEAD of Junior Research Group "Minnow"

Tel: +49 228 9122-367

Fax: +49 228 9122-212

E-Mail: M.Stange [at] leibniz-lib.de

Ph.D. student

Temitope Oriowo

PhD student

E-Mail: T.Oriowo [at] leibniz-lib.de

PhD Student

Tel: +49 228 9122-368

Fax: +49 228 9122-212

E-Mail: n.sternberg [at] leibniz-lib.de

Projects

2021

Hybrid swarm evolution in minnows

In biodiversity research, little is known so far about how hybridizations of a native and a non-native species can lead to the evolution of an invasive hybrid. A group of researchers led by Dr Madlen Stange is now studying this aspect in a project at the Zoological Research Museum Alexander Koenig – Leibniz Institute for Animal Biodiversity (ZFMK). The group is investigating the spread of Phoxinus, an ecologically important schooling fish, in the River Sieg, a 155 km tributary of the River Rhine.

Project lead:

Dr. Madlen Stange

Funding:

Leibniz Association

Publications

Published in

2023

Oriowo T, Chrysostomakis I, Martin S, Kukowka S, Brown T, Winkler S, Myers EW, Böhne A and Stange M. (2023) A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus) provide evidence of haplotype diversity. bioRxiv 2023.11.30.569369. doi: 10.1101/2023.11.30.569369

Links:

A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus)

2022

Bishop, C.E., Gahm K., Hendry, A.P., Jones, S.E., Stange, M., Solomon, C.T. (2022): Benthic–limnetic morphological variation in fishes: Dissolved organic carbon concentration produces unexpected patterns - Ecosphere (13): e3965. doi:10.1002/ecs2.3965

Brüningk, S. C. , Klatt, J., Stange, M., Mari, A., Brunner, M., Roloff, T-C., et al. (2022): Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area. Virus Evolution 8(1): veac002. doi:10.1093/ve/veac002

Kathrin Zürcher, Irene A Abela, Madlen Stange, Carole Dupont, Catrina Mugglin, Adrian Egli, Alexandra Trkola, Matthias Egger, Lukas Fenner, Alpha variant coronavirus outbreak in a nursing home despite high vaccination coverage: molecular, epidemiological and immunological studies, Clinical Infectious Diseases, 2022;, ciab1005, https://doi.org/10.1093/cid/ciab1005

Nadeau, S. A., Vaughan, T. G., Beckmann, C., Topolsky, I., Chen, C., Hodcroft, E., Schär, T., Nissen, I., Santacroce, N., Burcklen, E., Ferreira, P., Jablonski, K. P., Posada-Céspedes, S., Capece, V., Seidel, S., Santamaria de Souza, N., Martinez-Gomez, J. M., Cheng, P., Bosshard, P. P., Levesque, M. P., Kufner, V., Schmutz, S., Zaheri, M., Huber, M., Trkola, A., Cordey, S., Laubscher, F., Gonçalves, A. R., Aeby, S., Pillonel, T., Jacot, D., Bertelli, C., Greub, G., Leuzinger, K., Stange, M., Mari, A., Roloff, T., Seth-Smith, H., Hirsch, H. H., Egli, A., Redondo, M., Kobel, O., Noppen, C., du Plessis, L., Beerenwinkel, N., Neher, R. A., Beisel, C., Stadler, T. Swiss Public Health Measures Associated with Reduced SARS-CoV-2 Transmission Using Genome Data. Science Translational Medicine 2022, eabn7979. https://doi.org/10.1126/scitranslmed.abn7979.

2021

Wegner, F., Roloff, T., Huber, M., Cordey, S., Ramette, A., Gerth, Y., Bertelli, C., Stange, M., Seth-Smith, H., Mari, A., Leuzinger, K., Cerutti, L., Harshman, K., Xenarios, I., Le Mercier, P., Bittel, P., Neuenschwander, S., Opota, O., Fuchs, J., Panning, M., … Egli, A. (2021). External quality assessment of SARS-CoV-2-sequencing: An ESGMD-SSM pilot trial across 15 European laboratories. Journal of clinical microbiology, JCM0169821. Advance online publication. https://doi.org/10.1128/JCM.01698-21

Chen, C., Nadeau, S. A., Topolsky, I., Manceau, M., Huisman, J. S., Jablonski, K. P., Fuhrmann, L., ..., Stange, M., et. al. (2021): Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland. Epidemics, 37, 100480. https://doi.org/10.1016/j.epidem.2021.100480

Goncalves Cabecinhas, A.R., Roloff, T., Stange, M., Bertelli, C., Huber, M., Ramette, A., Chen, C., et. al. (2021): SARS-CoV-2 N501Y Introductions and Transmissions in Switzerland from Beginning of October 2020 to February 2021—Implementation of Swiss-Wide Diagnostic Screening and Whole Genome Sequencing. Microorganisms, 9, 677. https://doi.org/10.3390/microorganisms9040677

Fox J, Jiménez M.A., Stange M. Natural history study of an understudied sea catfish species from Panama (Siluriformes: Ariidae). Neotrop Ichthyol. 2021; 19(4):e200105. https://doi.org/10.1590/1982-0224-2020-0105

Mari, A., Roloff, T., Stange, M., Søgaard, K.K., Asllanaj, E., Tauriello, G., Alexander, et. al. (2021): A. Global Genomic Analysis of SARS-CoV-2 RNA Dependent RNA Polymerase Evolution and Antiviral Drug Resistance. Microorganisms, 9, 1094. https://doi.org/10.3390/microorganisms9051094

Stange, M., Barrett, R.D.H. & Hendry, A.P. The importance of genomic variation for biodiversity, ecosystems and people. Nat Rev Genet 22, 89–105 (2021). https://doi.org/10.1038/s41576-020-00288-7

Stange, M., Mari, A., Roloff, T., Seth-Smith, H. M. B., Schweitzer, M., Brunner, M., Leuzinger, K., et al. (2021) SARS-CoV-2 outbreak in a tri-national urban area is dominated by a B.1 lineage variant linked to a mass gathering event. PLOS Pathogens 17(3): e1009374. https://doi.org/10.1371/journal.ppat.1009374

2019

Heck, L., Sanchez-Villagra, M. R., Stange, M. (2019): Why the long face? Comparative shape analysis of miniature, pony, and other horse skulls reveals changes in ontogenetic growth. PeerJ 7:e7678 https://doi.org/10.7717/peerj.7678

2018

Heck, L., Wilson, L. A. B., Evin, A., Stange, M., Sánchez-Villagra, M. R. (2018): Shape variation and modularity of skull and teeth in domesticated horses and wild equids. Front Zool 15, 14. https://doi.org/10.1186/s12983-018-0258-9

Stange, M., Aguirre-Fernández, G., Salzburger, W., Sánchez-Villagra, M.R. (2018): Study of morphological variation of northern Neotropical Ariidae reveals conservatism despite macrohabitat transitions. BMC Evol Biol 18, 38 (2018). https://doi.org/10.1186/s12862-018-1152-y

Stange, M., Núñez-León, D., Sánchez-Villagra, M. R., Jensen, P., & Wilson, L. A. B. (2018): Morphological variation under domestication: how variable are chickens? Royal Society Open Science, 5(8), 180993. https://doi.org/10.1098/rsos.180993

Stange, M., Sánchez-Villagra, M. R., Salzburger, W., & Matschiner, M. (2018): Bayesian Divergence-Time Estimation with Genome-Wide Single-Nucleotide Polymorphism Data of Sea Catfishes (Ariidae) Supports Miocene Closure of the Panamanian Isthmus, Systematic Biology, Volume 67, Issue 4, 681–699, https://doi.org/10.1093/sysbio/syy006

2016

Stange, M., Aguirre-Fernández, G., Cooke, R.G., Barros, T., Salzburger, W. and Sánchez-Villagra, M.R. (2016), Evolution of opercle bone shape along a macrohabitat gradient: species identification using mtDNA and geometric morphometric analyses in neotropical sea catfishes (Ariidae). Ecol Evol, 6: 5817-5830. https://doi.org/10.1002/ece3.2334

2015

Fuchs, M., Geiger, M., Stange, M., Sánchez-Villagra, M. R. (2015): Growth trajectories in the cave bear and its extant relatives: an examination of ontogenetic patterns in phylogeny. BMC Evol Biol 15, 239. https://doi.org/10.1186/s12862-015-0521-z

2013

Mateus, C. S., Stange, M., Berner, D., Roesti, M., Quintella, B. R., Alves, M. J., Almeida, P. R., & Salzburger, W. (2013): Strong genome-wide divergence between sympatric European river and brook lampreys. Current Biology, 23(15), R649–R650. https://doi.org/10.1016/j.cub.2013.06.026